 | June 1, 2010 By:Howard Mark, Jerome Workman
The authors continue their discussion of the classical least squares approach to calibration.
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 | May 1, 2010 By:Howard Mark, Jerome Workman
In this month's installment of "Chemometrics in Spectroscopy," the authors begin a new subseries with the goal of explaining the classical least squares algorithm.
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 | February 1, 2010 By:Howard Mark, Jerome Workman Jr.
This installment of "Chemometrics in Spectroscopy" illustrates the various graphical ways used to observe and interpret comparative clinical quantitative measurement methods.
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 | June 1, 2009 By:Jerome Workman, Jr., Howard Mark
This article describes the application of chemometric methods and statistics for reporting clinical quantitative measurement methods. The equations and terminology are consistent with the Clinical and Laboratory Standards Institute (CLSI) guidelines. These chemometric and statistical methods describe the accuracy and precision of a test method compared to a reference method for a single analyte determination. Part I will introduce these concepts and Part II will discuss the statistical underpinnings in greater detail.
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 | May 1, 2009 By:Howard Mark, Jerome Workman, Jr.
Columnists Howard Mark and Jerome Workman, Jr. take a final look at the topic of principal components, which has been the subject of six previous installments.
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 | February 1, 2009 By:Howard Mark, Jerome Workman, Jr.
This column is a continuation of the set we have been working on to explain and derive the equations behind principal components (1–5). As we usually do, when we continue the discussion of a topic through more than one column, we continue the numbering of equations from where we left off.
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 | October 1, 2008 By:Jerome Workman, Jr., Howard Mark
For a system of homogeneous equations to have a solution other than the trivial solution, the determinant of the system of equations must be zero.
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 | June 1, 2008 By:Howard Mark, Jerome Workman, Jr.
Howard Mark and Jerome Workman, Jr. continue their discussion of the derivation of the principal component algorithm using elementary algebra.
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 | May 1, 2008 By:Howard Mark, Jerome Workman, Jr.
Howard Mark and Jerome Workman, Jr. continue their discussion of the derivation of the principal component algorithm using elementary algebra.
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